IT'S YOUR SKIN
If you’re looking at TREMFYA® as a treatment option for your moderate to severe plaque psoriasis, let us help. The first FDA-approved medication of its kind, TREMFYA® selectively blocks interleukin-23 (IL-23), one of the key proteins thought to be responsible for the symptoms of plaque psoriasis.
Let’s talk about clearer skin
If you’ve tried steroids, topical creams or phototherapy and still didn’t get the results you wanted, TREMFYA® may be the treatment for you.
Individual results may vary.
UNCOVER CLEARER SKIN
In clinical studies at 16 weeks, at least 7 out of 10 patients with moderate to severe plaque psoriasis saw at least 90% clearer skin and more than 8 out of 10 were rated clear or almost clear.
SUPERIOR SKIN CLEARANCE
In clinical studies, TREMFYA® was proven superior to Humira® (adalimumab) in providing clearer skin.*
*Results are reflective of patients studied in the United States and Canada.
Humira® (adalimumab) is a registered trademark of AbbVie Inc.
PLAQUE PSORIASIS SYMPTOMS
More people using TREMFYA® were free from symptoms, including itching, skin tightness, burning, stinging, and pain at 24 weeks compared with those using Humira®.
Individual results may vary.
TREMFYA® is given as a single 100 mg injection under your skin once every 8 weeks, after 2 starter doses at weeks 0 and 4. That means you don’t have to think about your next scheduled maintenance dose for almost two months between injections.
FIRST 52 WEEKS OF THERAPY
Humira® is a prescription medication used to treat adults with moderate to severe chronic plaque psoriasis who are ready for systemic therapy or phototherapy, and are under the care of a doctor who will decide if other systemic therapies are less appropriate.
The exact cause of plaque psoriasis is unknown. However, we do know that the immune system, environmental factors, and family history can play a role. The immune system sends faulty signals causing skin cells to grow too quickly. New skin cells form in days rather than weeks, causing cells to pile up on the surface of the skin and form psoriatic plaques.
Your doctor will prescribe a plaque psoriasis treatment for you based on how severe your condition is, how much of your body is affected, where your plaque psoriasis is on your body, and your medical history.
- Topical Creams: Used directly on the surface of your skin and are usually the first treatment considered.
- Phototherapy or Light Therapy: Your skin, or just the psoriatic plaque, is exposed to ultraviolet light (UVB rays or psoralen plus UVA rays [PUVA]) on a regular basis and under medical supervision.
- Biologics (for moderate to severe plaque psoriasis): Injectable treatments that target specific proteins within your body that may play a key role in your plaque psoriasis.
- Oral systemic therapies: Pills that work either throughout the body or on specific inflammatory cells thought to affect the process of plaque psoriasis.
TREMFYA® is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light or UV light).
TREMFYA® is administered as a single 100 mg injection under the skin at weeks 0 and 4, and then every 8 weeks. It is administered by a healthcare provider or self-injected only after proper training.
Only your doctor can decide how long you should continue treatment with TREMFYA®.
No. TREMFYA® is not a steroid. TREMFYA® is a biologic that works to target an overactive immune system, a possible cause of plaque psoriasis. It blocks the action of interleukin-23, or IL-23, one of the proteins that may play a role in plaque psoriasis.
The active ingredient in TREMFYA® is called guselkumab. TREMFYA® is manufactured by Janssen Biotech, Inc., Horsham, PA 19044, U.S. License No. 1864.
TREMFYA® is not for everyone; only your doctor can decide if it’s right for you. Do not use if you are allergic to TREMFYA®. TREMFYA® is a prescription medicine that may cause serious side effects, including serious allergic reactions and infections. TREMFYA® affects your immune system. It may increase your risk of infections and lower your ability to fight them. Please read the Important Safety Information below and the Medication Guide for TREMFYA® to learn more about these and other risks for TREMFYA®. Discuss any questions you have with your doctor.
The most common side effects of TREMFYA® include: upper respiratory infections, headache, injection site reactions, joint pain (arthralgia), diarrhea, stomach flu (gastroenteritis), fungal skin infections, herpes simplex infections, and bronchitis.
These are not all the possible side effects of TREMFYA®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
You should not receive a live vaccine while taking TREMFYA®. Before receiving TREMFYA®, tell your doctor if you have recently received or are scheduled to receive an immunization (vaccine). It is important to read the Important Safety Information located on this website.
Everyone responds to treatment differently. But in clinical studies, at least 7 out of 10 patients on TREMFYA® saw at least 90% clearer skin at week 16, after just 3 doses (weeks 0, 4, and 12). And in that same time, more than 8 out of 10 patients were rated clear or almost clear. In a clinical study, most patients who saw 90% clearer skin at 28 weeks stayed clearer through 48 weeks. In another clinical study, nearly 7 out of 10 patients with 90% clearer skin at 16 weeks were still clearer at 5 years. At 1 year and thereafter, patients and healthcare providers knew that TREMFYA® was being used. This may have increased results. Results may vary.
TREMFYA® must be stored in the refrigerator at 36° F to 46° F (2° C to 8° C). Do not freeze and do not shake. Keep TREMFYA® prefilled syringe or One-Press injector in the original carton to protect from light and physical damage until time of use. TREMFYA® is sterile and preservative free. Discard any unused portion. Keep TREMFYA® prefilled syringe or One-Press injector, and all medicines, out of reach of children. If your TREMFYA® medication has been stored outside of the recommended temperature ranges, contact Janssen Medical Information at 1-800-JANSSEN (1-800-526-7736) for more information.
Safe Returns® is a simple, safe, and convenient way to dispose of your used syringes or One-Press Injector – at no additional cost to you. When you sign up, you’ll receive a Safe Returns® plastic disposal container in the mail, along with simple mail-back instructions. Call 877-CarePath (877-227-3728), Monday—Friday, 8:00 AM to 8:00 PM ET to sign up for the Safe Returns® program or sign up online.
You can receive your injections at your dermatologist’s office, or you or your caregiver can be trained to give them at home after proper training in subcutaneous injection technique by your healthcare provider.
The fluid in the prefilled syringe or in the One-Press device should be clear to slightly yellow and may contain tiny white or clear particles. You may also see one or more air bubbles. This is normal. Do not inject if the liquid is cloudy or discolored, or has large particles. Call your healthcare provider or pharmacist for a refill. If you have questions about injections, talk to your dermatologist.
Whether you're using a prefilled syringe or the One-Press device, you can use areas of the body like the front of your thighs (recommended), or your lower stomach area (lower abdomen). Just remember, the 2-inch radius around your belly button must be avoided. If you've got someone there to help you out, the back of your upper arm is also an option. Make sure you don't inject into skin that is tender, bruised, red, hard, thick, scaly, or affected by psoriasis. If you have questions about injections, talk to your dermatologist.
There may be a small amount of blood or liquid at the injection site. Hold pressure over your skin with a cotton ball or gauze pad until any bleeding stops. Do not rub the injection site. If needed, cover injection site with a bandage. If you have questions about injections, talk to your dermatologist.
Put your used TREMFYA® syringe or One-Press injector in an FDA-cleared sharps disposal container right away after use. Do not throw away your TREMFYA® prefilled syringe or One-Press injector in your household trash.
Do not recycle your used sharps disposal container.
For more information, see “How should I dispose of the used prefilled syringe?” in the Instructions For Use for TREMFYA®.
Safe Returns® is a simple, safe, and convenient way to dispose of your used syringes or One-Press Injector—at no additional cost to you. When you sign up, you’ll receive a Safe Returns® plastic disposal container in the mail, along with simple mail-back instructions.
Call 877-CarePath (877-227-3728), Monday—Friday, 8:00 AM to 8:00 PM ET to sign up for the Safe Returns® program or sign up online. If you have any questions about injections, talk to your doctor.
If you miss your TREMFYA® dose, inject a dose as soon as you remember. Then, take your next dose at your regular scheduled time. If you’re not sure what to do, or have questions about injections, talk to your dermatologist.
Understanding your insurance coverage can be tricky. Since coverage policies can vary from plan to plan, it’s important to check if your pharmacy and medical benefits cover TREMFYA®. Your dedicated TREMFYA withMe Guide can help you verify your insurance benefits and learn about your insurance coverage for TREMFYA®. You can contact TREMFYA withMe at 1-833-WITHME1 (948-4631) Monday through Friday from 8:00 AM to 11:00 PM ET